Overview
SCIENTIFIC SCORE
Questionable
Based on 14 Researches
6.5
USERS' SCORE
Moderately Good
Based on 2 Reviews
7.3
Top Medical Research Studies
9.5
We observed a fascinating case involving a male in his 40s who experienced persistent inflammatory back pain for three months. Despite having a negative test for HLA-B27, a marker often associated with axial spondyloarthritis, clinical assessments suggested possible underlying issues.
The clinical investigation led to an MRI, which confirmed bilateral symmetrical sacroiliitis. Interestingly, further tests showed he had very low vitamin D levels along with elevated parathyroid hormone—indicating a possible deficiency impacting his condition.
After starting treatment with vitamin D alongside nonsteroidal anti-inflammatory drugs (NSAIDs), he experienced notable relief from his symptoms. His condition improved significantly, and follow-up tests indicated that his vitamin D levels had normalized.
This case demonstrates the potential benefits of vitamin D in managing back pain, especially when classical markers are inconclusive. It highlights how a thorough diagnosis can reveal interconnected health issues and improve treatment outcomes.
The clinical investigation led to an MRI, which confirmed bilateral symmetrical sacroiliitis. Interestingly, further tests showed he had very low vitamin D levels along with elevated parathyroid hormone—indicating a possible deficiency impacting his condition.
After starting treatment with vitamin D alongside nonsteroidal anti-inflammatory drugs (NSAIDs), he experienced notable relief from his symptoms. His condition improved significantly, and follow-up tests indicated that his vitamin D levels had normalized.
This case demonstrates the potential benefits of vitamin D in managing back pain, especially when classical markers are inconclusive. It highlights how a thorough diagnosis can reveal interconnected health issues and improve treatment outcomes.
Read More
8
We conducted a randomized controlled trial to investigate how vitamin D supplementation might alleviate lower back pain in patients suffering from lumbar spinal stenosis. This study involved patients with severely low vitamin D levels, specifically under 10 ng/mL. Participants were divided into two groups: one received vitamin D supplements, while the other did not.
Over a period of several weeks, we measured pain levels and functional recovery using simple questionnaires and health surveys. Notably, we observed that those who received vitamin D injections reported significant improvements in their back pain and overall quality of life compared to those who didn’t.
Our findings suggest that addressing vitamin D deficiency might play a crucial role in managing back pain for individuals with spinal stenosis who are not candidates for surgical intervention. The results demonstrate a promising correlation between high-dose vitamin D supplementation and enhanced functional outcomes in these patients.
Over a period of several weeks, we measured pain levels and functional recovery using simple questionnaires and health surveys. Notably, we observed that those who received vitamin D injections reported significant improvements in their back pain and overall quality of life compared to those who didn’t.
Our findings suggest that addressing vitamin D deficiency might play a crucial role in managing back pain for individuals with spinal stenosis who are not candidates for surgical intervention. The results demonstrate a promising correlation between high-dose vitamin D supplementation and enhanced functional outcomes in these patients.
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4
We conducted a year-long study to investigate the effects of vitamin C on postoperative pain and recovery after a specific type of spine surgery known as posterior lumbar interbody fusion (PLIF). In this randomized, placebo-controlled trial, we worked with 123 patients, dividing them into two groups: one receiving vitamin C and the other a placebo.
Our main focus was to see how vitamin C influenced lower back pain measured by a visual analogue scale. While we found that there was no significant difference in pain levels at the one-year mark between the two groups, there was a silver lining. We observed that vitamin C appeared to enhance functional improvement, especially within the first three months after surgery.
So, while vitamin C didn’t seem to directly reduce pain intensity after surgery, it could play a role in supporting early recovery and everyday function. This finding may encourage further exploration into vitamin C's potential benefits in postoperative care for patients undergoing spine surgeries.
Our main focus was to see how vitamin C influenced lower back pain measured by a visual analogue scale. While we found that there was no significant difference in pain levels at the one-year mark between the two groups, there was a silver lining. We observed that vitamin C appeared to enhance functional improvement, especially within the first three months after surgery.
So, while vitamin C didn’t seem to directly reduce pain intensity after surgery, it could play a role in supporting early recovery and everyday function. This finding may encourage further exploration into vitamin C's potential benefits in postoperative care for patients undergoing spine surgeries.
Read More
Most Useful Reviews
0
Severe headaches experienced
20 people found this helpful
I encountered severe headaches, muscle cramps, and other symptoms while taking this product. After ceasing use for a few days, my symptoms disappeared, but upon a smaller dose, headaches returned. I experienced difficulties sleeping and severe aches, attributing it to incorrect timing of ingestion. Despite my initial hopes for these vitamins, the negative effects far outweighed any potential benefits, leading me to discontinue their use.
Read More
7.5
Active lifestyle restored
1 people found this helpful
After two weeks of using this product as directed, I can confidently say it works. As someone who has been active my entire life, I faced constant injuries that hindered my performance. I discovered a product that alleviated my joint and tendon pain, allowing me to resume training. I've transitioned from a one-class-a-week regimen to three weekly classes. I feel a significant difference and can now train pain-free.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 14 Researches
6.5
- All Researches
9.5
We observed a fascinating case involving a male in his 40s who experienced persistent inflammatory back pain for three months. Despite having a negative test for HLA-B27, a marker often associated with axial spondyloarthritis, clinical assessments suggested possible underlying issues.
The clinical investigation led to an MRI, which confirmed bilateral symmetrical sacroiliitis. Interestingly, further tests showed he had very low vitamin D levels along with elevated parathyroid hormone—indicating a possible deficiency impacting his condition.
After starting treatment with vitamin D alongside nonsteroidal anti-inflammatory drugs (NSAIDs), he experienced notable relief from his symptoms. His condition improved significantly, and follow-up tests indicated that his vitamin D levels had normalized.
This case demonstrates the potential benefits of vitamin D in managing back pain, especially when classical markers are inconclusive. It highlights how a thorough diagnosis can reveal interconnected health issues and improve treatment outcomes.
The clinical investigation led to an MRI, which confirmed bilateral symmetrical sacroiliitis. Interestingly, further tests showed he had very low vitamin D levels along with elevated parathyroid hormone—indicating a possible deficiency impacting his condition.
After starting treatment with vitamin D alongside nonsteroidal anti-inflammatory drugs (NSAIDs), he experienced notable relief from his symptoms. His condition improved significantly, and follow-up tests indicated that his vitamin D levels had normalized.
This case demonstrates the potential benefits of vitamin D in managing back pain, especially when classical markers are inconclusive. It highlights how a thorough diagnosis can reveal interconnected health issues and improve treatment outcomes.
Read More
9
We conducted a retrospective review to uncover how vitamin D treatment impacts back pain in individuals diagnosed with adult-onset hypophosphatemic osteomalacia. In our exploration, we found that eight patients, primarily experiencing widespread musculoskeletal pain, were assessed over a span from January 2011 to December 2019.
Each patient presented with low phosphorus levels, elevated alkaline phosphatase, and indicative imaging results. Notably, back pain was reported as the most common complaint, along with muscle weakness in over half of the cases. Our findings highlighted the effectiveness of vitamin D in tandem with phosphorus supplementation, as all patients reported significant improvements in pain, muscle strength, and gait after receiving treatment.
Importantly, we noted that the specific diagnosis of each patient varied. In six cases, treatment was prompted by adefovir-induced Fanconi syndrome, while the remaining two patients had tumor-induced osteomalacia and light-chain nephropathy. This variation indicates the diverse etiologies of hypophosphatemic osteomalacia, further emphasizing the importance of targeted treatment based on individual needs.
In conclusion, our study suggests that vitamin D, especially when combined with phosphorus, plays a crucial role in alleviating back pain associated with this condition. By enhancing the understanding of the relationship between vitamin D treatment and back pain, we aim to shed light on effective management strategies for those suffering from similar symptoms.
Each patient presented with low phosphorus levels, elevated alkaline phosphatase, and indicative imaging results. Notably, back pain was reported as the most common complaint, along with muscle weakness in over half of the cases. Our findings highlighted the effectiveness of vitamin D in tandem with phosphorus supplementation, as all patients reported significant improvements in pain, muscle strength, and gait after receiving treatment.
Importantly, we noted that the specific diagnosis of each patient varied. In six cases, treatment was prompted by adefovir-induced Fanconi syndrome, while the remaining two patients had tumor-induced osteomalacia and light-chain nephropathy. This variation indicates the diverse etiologies of hypophosphatemic osteomalacia, further emphasizing the importance of targeted treatment based on individual needs.
In conclusion, our study suggests that vitamin D, especially when combined with phosphorus, plays a crucial role in alleviating back pain associated with this condition. By enhancing the understanding of the relationship between vitamin D treatment and back pain, we aim to shed light on effective management strategies for those suffering from similar symptoms.
Read More
9
We explored a study that investigated the effects of zinc supplementation on bone density in individuals with beta-thalassaemia and its potential influence on back pain. The research did not specifically isolate the impact of zinc on back pain, which makes it challenging to draw definitive conclusions about its effectiveness for this particular issue.
While the study showed significant increases in bone mineral density at the lumbar spine after 12 and 18 months of zinc treatment, it did not provide detailed information regarding any changes in back pain associated with these improvements.
There was also no mention of fractures related to back pain reduction, nor were adverse effects reported in the zinc supplementation trial. Thus, it leaves us with the understanding that, while zinc may help with bone density, its direct impact on alleviating back pain remains unclear. Further research would be necessary to clarify any connections.
While the study showed significant increases in bone mineral density at the lumbar spine after 12 and 18 months of zinc treatment, it did not provide detailed information regarding any changes in back pain associated with these improvements.
There was also no mention of fractures related to back pain reduction, nor were adverse effects reported in the zinc supplementation trial. Thus, it leaves us with the understanding that, while zinc may help with bone density, its direct impact on alleviating back pain remains unclear. Further research would be necessary to clarify any connections.
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8
We examined how Vitamin C, when combined with other supplements, could help manage chronic low back pain (LBP), especially in patients dealing with lumbar osteoarthritis. In our study, we divided sixty participants into two groups: one that received physical therapy alone and another that combined this therapy with a daily intake of Fortigel® and additional nutrients like Vitamin C, sodium hyaluronate, manganese, and copper.
Over the treatment period, we assessed the participants' pain levels, disability, and overall quality of life at three different times: at the start of the study, at the end of the initial treatment, and about a month later.
The results suggested that the group taking the additional supplements experienced significant improvements in pain relief and rehabilitation benefits compared to those who relied solely on exercise. However, since Vitamin C was part of a combination with other nutrients, its individual impact on back pain remains unclear. Thus, while overall results are promising, the specific benefit of Vitamin C in isolation can't be stated with certainty.
Over the treatment period, we assessed the participants' pain levels, disability, and overall quality of life at three different times: at the start of the study, at the end of the initial treatment, and about a month later.
The results suggested that the group taking the additional supplements experienced significant improvements in pain relief and rehabilitation benefits compared to those who relied solely on exercise. However, since Vitamin C was part of a combination with other nutrients, its individual impact on back pain remains unclear. Thus, while overall results are promising, the specific benefit of Vitamin C in isolation can't be stated with certainty.
Read More
8
Effectiveness of combined treatments
We explored how a combination of treatments, including a specific vitamin D supplement (Cholecalciferol), could help alleviate back pain in young people suffering from sciatica due to herniated discs. In this study, we looked at 128 patients divided into three groups. One group received a combination of rehabilitation therapy and daily supplements, while the second group only underwent rehabilitation. The third group was given supplements without the additional therapy.
Over a span of 60 days, we measured improvements in pain levels, disability, and quality of life using various rating scales. We found that the group receiving both rehabilitation and supplements saw significant improvements in pain and overall quality of life after 30 days. However, after two months, while they still had better outcomes in pain and quality of life compared to the other groups, the vitamin D's individual effect couldn’t be distinctly isolated.
Ultimately, our findings suggest that while vitamin D was part of an effective treatment plan that included other beneficial supplements, we cannot attribute all the improvements in back pain directly to vitamin D alone. This highlights the importance of comprehensive treatment approaches for conditions like sciatica.
Over a span of 60 days, we measured improvements in pain levels, disability, and quality of life using various rating scales. We found that the group receiving both rehabilitation and supplements saw significant improvements in pain and overall quality of life after 30 days. However, after two months, while they still had better outcomes in pain and quality of life compared to the other groups, the vitamin D's individual effect couldn’t be distinctly isolated.
Ultimately, our findings suggest that while vitamin D was part of an effective treatment plan that included other beneficial supplements, we cannot attribute all the improvements in back pain directly to vitamin D alone. This highlights the importance of comprehensive treatment approaches for conditions like sciatica.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 2 Reviews
7.3
- All Reviews
- Positive Reviews
- Negative Reviews
0
Severe headaches experienced
20 people found this helpful
I encountered severe headaches, muscle cramps, and other symptoms while taking this product. After ceasing use for a few days, my symptoms disappeared, but upon a smaller dose, headaches returned. I experienced difficulties sleeping and severe aches, attributing it to incorrect timing of ingestion. Despite my initial hopes for these vitamins, the negative effects far outweighed any potential benefits, leading me to discontinue their use.
Read More
7.5
Active lifestyle restored
1 people found this helpful
After two weeks of using this product as directed, I can confidently say it works. As someone who has been active my entire life, I faced constant injuries that hindered my performance. I discovered a product that alleviated my joint and tendon pain, allowing me to resume training. I've transitioned from a one-class-a-week regimen to three weekly classes. I feel a significant difference and can now train pain-free.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Farì G, Santagati D, Pignatelli G, Scacco V, Renna D, et al. Collagen Peptides, in Association with Vitamin C, Sodium Hyaluronate, Manganese and Copper, as Part of the Rehabilitation Project in the Treatment of Chronic Low Back Pain. Endocr Metab Immune Disord Drug Targets. 2022;22:108. doi:10.2174/1871530321666210210153619
- Lee GW, Yang HS, Yeom JS, Ahn MW. The Efficacy of Vitamin C on Postoperative Outcomes after Posterior Lumbar Interbody Fusion: A Randomized, Placebo-Controlled Trial. Clin Orthop Surg. 2017;9:317. doi:10.4055/cios.2017.9.3.317
- Dionne CE, Laurin D, Desrosiers T, Abdous B, Le Sage N, et al. Serum vitamin C and spinal pain: a nationwide study. Pain. 2016;157:2527. doi:10.1097/j.pain.0000000000000671
- Ahmed S, Shah Z, Ali N. Chronic low backache and stiffness may not be due ankylosing spondylitis. J Pak Med Assoc. 2010;60:681.
- Lee TJ, Tsai RY, Ho CC, Chen CM, Li CP. Updated Meta-analysis Reveals Limited Efficacy of Vitamin D Supplementation in Chronic Low Back Pain. In Vivo. 2024;38:2955. doi:10.21873/invivo.13778
- Bose S, Mohanasundaram K, Rajalakshmi KV, Perumal Kumaresan A, Simon J. An Unusual Mimic of Axial Spondyloarthritis: A Case Report. Cureus. 2024;16:e61441. doi:10.7759/cureus.61441
- V N, Nair GG, Jose BC, Abraham A. Study on Vitamin D Levels in 30 to 40-Year-Old Females With Low Back Pain. Cureus. 2024;16:e54238. doi:10.7759/cureus.54238
- Scaturro D, Vitagliani F, Tomasello S, Sconza C, Respizzi S, et al. Combined Rehabilitation with Alpha Lipoic Acid, Acetyl-L-Carnitine, Resveratrol, and Cholecalciferolin Discogenic Sciatica in Young People: A Randomized Clinical Trial. Medicina (Kaunas). 2023;59. doi:10.3390/medicina59122197
- Kim S, Kim SW, Lee BC, Kim DH, Sung DH. Adult-onset hypophosphatemic osteomalacia as a cause of widespread musculoskeletal pain: A retrospective case series of single center experience. World J Clin Cases. 2023;11:7785. doi:10.12998/wjcc.v11.i32.7785
- Ko S, Kim HC, Kwon J. The effectiveness of vitamin D3 supplementation in improving functional outcome of non-surgically treated symptomatic lumbar spinal stenosis: Randomized controlled clinical trial - Pilot study. Medicine (Baltimore). 2023;102:e32672. doi:10.1097/MD.0000000000032672
- Evangelatos G, Kouna K, Iliopoulos A, Fragoulis GE. Musculoskeletal Complications of Celiac Disease: A Case-Based Review. Mediterr J Rheumatol. 2023;34:86. doi:10.31138/mjr.34.1.86
- Dechsupa S, Yingsakmongkol W, Limthongkul W, Singhatanadgige W, Jitjumnong M, et al. Vitamin D Inadequacy Affects Skeletal Muscle Index and Physical Performance in Lumbar Disc Degeneration. Int J Mol Sci. 2023;24. doi:10.3390/ijms24043152
- Bhardwaj A, Swe KMM, Sinha NK. Treatment for osteoporosis in people with beta-thalassaemia. Cochrane Database Syst Rev. 2023;5:CD010429. doi:10.1002/14651858.CD010429.pub3
- Bhardwaj A, Swe KM, Sinha NK, Osunkwo I. Treatment for osteoporosis in people with ß-thalassaemia. Cochrane Database Syst Rev. 2016;3:CD010429. doi:10.1002/14651858.CD010429.pub2
